IC50 values for selected proteinase inhibitors following preincubation for 30 min with chymase, cathepsin G, or chymotrypsin
| Inhibitor | IC50values | ||
|---|---|---|---|
| Chymase | Cathepsin G | Chymotrypsin | |
| nM | |||
| ZIGPFM | 42 | 920 | 150 |
| Chymostatin | 420 | 12,000 | 94 |
| SBTI | 125 | 20 | 425 |
| Aprotinin | N.I. | 1,100 | 83 |
Mean values are presented for assays with 0.7 mM AAPFpNA conducted in triplicate experiments.
N.I., no inhibition.