Summary of PD profile of dexmedetomidine determined by the estimated EC50 values for all stimulus-response and continuous measurements
| PD Measure | EC50 |
|---|---|
| ng/ml | |
| Bradycardia | 0.51 ± 0.04 |
| EEG | 1.02 ± 0.08 |
| Whisker reflex | 1.09 ± 0.10 |
| Sympathoadrenal block | 1.85 ± 0.80 |
| Increase in MAP | 1.90 ± 0.48 |
| Righting reflex | 2.13 ± 0.15 |
| Tail flick | 3.65 ± 0.87 |
| Startle reflex | 3.75 ± 0.64 |
| Tail clamp | 5.49 ± 1.34 |
| Corneal reflex | 24.5 ± 12.3 |
Values are mean ± S.E.