Table 1

Behavioral scores for MK-801-induced locomotion, stereotyped sniffing, and ataxia in rats

BehaviorScoreCharacteristic
Locomotion1-a 0Stationary
1Movements within a localized area, forelimbs only
2Intermittent movements within half of the area of the cage
3Continuous movements within half of the area of the cage
4Intermittent movements within the whole area of the cage
5Continuous movements within the whole area of the cage
Stereotypy1-a 0No sniffing
1Discontinuous sniffing (free interval of more than 5 s)
2Continuous sniffing
Ataxia0Normal body control
1Falling tendency upon movement
2Falling upon movement
3Almost unable to move
  • 1-a The scores for locomotion and stereotyped sniffing are from the studies of Sturgeon and coworkers (1979) and Hoffman (1992), respectively.