Table 6

Effect of silibinin added 24 h before the chemical-induced injury on the proliferation of Vero kidney cells in the presence of 16.7 μM cisplatin

CisplatinSilibinin HemisuccinateFinal Cell ConcentrationsLiving CellsGrowth Rate
μM μM % %
 003.94  × 105 95100  ± 1.8
3.84  × 105 94
16.701.90  × 105 8950  ± 3.16-a
1.96  × 105 91
16.7202.40  × 105 8960  ± 3.16-a 6-150
2.30  × 105 90
16.7402.40  × 105 9163  ± 3.06-a 6-150
2.50  × 105 91
  • Included S.D. (n = 8) and statistical significances in comparison with the experiments with intoxication by cisplatin.

  • 6-150 p < .001.

  • 6-a Corresponding values.