Table 2

Influence of the main flavonolignans from Silybum marianumin concentrations of each 20 μM on the proliferation of Vero kidney cells

Final Cell ConcentrationLiving Cells Growth Rate
% %
Control4.26  × 105 95
4.34  × 105 96100  ± 1.5
Ethanol (1%)4.26  × 105 96
4.28  × 105 9699  ± 2.6
Silibinin4.96  × 105 96
4.98  × 105 96116  ± 2.5**
Silidianin4.10  × 105 96
4.92  × 105 9694  ± 3.02-150
Silicristin4.92  × 105 96
4.88  × 105 96114  ± 2.7**
Isosilibinin3.90  × 105 96
3.72  × 105 9590  ± 3.1**
  • Included S.D. (n = 8) and statistical significances in comparison with the untreated control.

  • 2-150 p < .01; **p < .001.