Table 3

Dose-response and plasma concentrations after p.o. administration of GP683

Dose	MES	Plasma Concentration^3-a
mg/kg	% Inhibition	ng/ml
1	12.5	80 ± 7
5	50	150 ± 10
20	75	380 ± 80
100	100	960 ± 110

↵3-a Mean ± S.E.M. for eight animals.