Table 3

Functional effects of SPD 502, NS 1219, NS 1220, and NBQX on AMPA-induced [³H]GABA release from cultured mouse cortical neurons

Compound	IC₅₀
	μM
SPD 502	0.23 ± 0.07
NS 1219	0.19 ± 0.04
NS 1220	0.34 ± 0.07
NBQX	0.19 ± 0.04

[³H]GABA release studies were performed in the presence of 5 μM AMPA as described in Experimental Procedures. Results are means ± S.E.M. of three to four separate determinations.