Time Interval Since Last INH dose | VEH-INH | BNPP-INH | t-test | |
---|---|---|---|---|
Plasma Hydrazine at 24 h (μM) | 15 h | 12.1 ± 4.6 | 6.1 ± 0.9 | p = .22 |
n = 153-a | n = 43-a | |||
Plasma Hydrazine at 32 h (μM) | 2 h | 31.8 ± 2.8 | 8.2 ± 1.8 | p < .00001 |
n = 14 | n = 133-a |
↵3-a Plasma hydrazine levels were below the quantitation limit (4 μM) in one animal in the VEH-INH group and 12 animals in the BNPP-INH group at 24 h and in three of the animals in the BNPP-INH group at 32 h.