Table 1

Protease inhibition profile of SLPI

EnzymeKi
nM
Chymotrypsin0.26
Elastase0.34
Tryptase0.58
Cathepsin G11.0
Trypsin23.6
Kallikrein (tissue)No inhibition at 83 μM
ThrombinNo inhibition at 83 μM
Factor XaNo inhibition at 100 μM
Kallikrein (plasma)No inhibition at 100 μM
PlasminNo inhibition at 100 μM