Comparison of resting membrane potential, membrane resistance, amplitude and half-width of spikes, sAHP, and spike-frequency adaptation of mPFC cells in preparations from the rats that received subchronic treatment with vehicle and PCP (1 week/48 to 60 h), respectively
| Conditions | Resting Membrane Potential | Membrane Resistance | Spike Amplitude | Spike half-width | sAHP2-a | Spike-Frequency Adaptation2-b |
|---|---|---|---|---|---|---|
| mV | MΩ | mV | ms | mV | ||
| Vehicle (n = 23) | −72.7 ± 0.5 | 54.5 ± 3.5 | 90.3 ± 1.7 | 1.2 ± 0.1 | 5.8 ± 0.6 | 3.3 ± 0.2 |
| PCP (n = 29) | −69.5 ± 0.62-150 | 46.4 ± 2.8 | 88.1 ± 1.5 | 1.1 ± 0.1 | 3.4 ± 0.32-150 | 5.1 ± 0.52-150 |
↵2-a Cells were held at −65 mV; sAHP was obtained by passing 0.1 nA through the recording microelectrode.
↵2-b Number of action potentials which were evoked by a depolarizing pulse 0.5 nA, 600 ms; cells were held at −70 mV.
↵2-150 Significantly different from those of the vehicle control group (p < .05, t tests with Bonferroni’s correction).