Ang and BK peptide levels in kidney, heart, aorta, and lung of vehicle-treated sham-operated rats and vehicle-treated rats with myocardial infarction
| Tissue | Ang II | Ang I | Ang II/Ang I ratio | BK-(1–7) | BK-(1–9) | BK-(1–7)/BK-(1–9) ratio |
|---|---|---|---|---|---|---|
| fmol/g | fmol/g | mol/mol | fmol/g | fmol/g | mol/mol | |
| Kidney | ||||||
| Sham | 111 ± 10 | 36 ± 4 | 3.4 ± 0.5 | 75 ± 10 | 87 ± 7 | 0.85 ± 0.08 |
| Infarct | 85 ± 8 | 45 ± 10 | 2.4 ± 0.4 | 44 ± 5a | 74 ± 8 | 0.63 ± 0.06a |
| Heart | ||||||
| Sham | 3.9 ± 0.9 | 1.5 ± 0.3 | 3.6 ± 1.2 | 32 ± 5 | 32 ± 6 | 1.10 ± 0.09 |
| Infarct | 10.7 ± 1.2b | 2.1 ± 0.5 | 8.1 ± 1.8a | 26 ± 4 | 23 ± 3 | 1.12 ± 0.07 |
| Aorta | ||||||
| Sham | 67 ± 12 | <20 | >3.4 | 38 ± 7 | 25 ± 9 | 2.8 ± 0.8 |
| Infarct | 89 ± 17 | <20 | >4.5 | 41 ± 17 | 45 ± 18 | 1.3 ± 0.3 |
| Lung | ||||||
| Sham | 67 ± 5 | 5.8 ± 1.8 | 19 ± 3 | 49 ± 7 | 58 ± 8 | 0.90 ± 0.10 |
| Infarct | 74 ± 11 | 3.9 ± 0.6 | 24 ± 6 | 25 ± 3b | 53 ± 7 | 0.48 ± 0.06b |
Each value represents mean ± S.E.M., n = 9 to 10/group. a P < 0.05,b P < 0.01 compared with sham-operated rats.