Percentage of mice exhibiting clonic convulsions after cocaine alone or in combination with non-seizurogenic doses of methamphetamine or sydnocarb
| Treatment | % Clonic Convulsions |
|---|---|
| Vehicle + 55 mg/kg cocaine | 19 |
| 10 mg/kg methamphetamine + 55 mg/kg cocaine | 633-a |
| 100 mg/kg sydnocarb + 55 mg/kg cocaine | 25 |
↵3-a Significant difference from the vehicle-cocaine control as calculated by Fisher’s exact test (p < .05). One mouse in this group died after the drug combination.