Characteristics of HSA and HBOC solutions
| HSA | Ao HBOC | O-Raffinose HBOC | |||
|---|---|---|---|---|---|
| Solution 1 | Solution 2 | Solution 3 | |||
| Concentration (g/dl) | 6.0 | 6.9 | 9.8 | 10.0 | 9.9 |
| Colloid oncotic pressure (mm Hg) | 20 | 24 | 22 | 23 | 22 |
| Methemoglobin (%) | NM | 4.7 | 4.1 | 5.0 | 4.9 |
| P50 (mm Hg) | NM | 14.6 | 45.5 | 44.9 | 44.1 |
| P50 slope (n) | NM | 2.24 | 1.32 | 1.55 | 1.72 |
| Dimeric hemoglobin content (% of total) | NA | 100 | 2.6 | 0.6 | 0.3 |
| Tetrameric hemoglobin content (% of total) | NA | 0 | 31.8 | 18.1 | 1.8 |
| Oligomerized hemoglobin content (% of total) | NA | 0 | 63.8 | 81.1 | 96.9 |
HBOC, hemoglobin-based oxygen-carrying solutions; NM, not measured; NA, not applicable.