Table 1

P values and IC50 values of n-TAA compounds

CompoundMW of Organic CationsP (octanol/water)Log(P)IC50
μM
TMA740.00021-a −3.699>10,000
TEA1300.00271-b −2.568260  ± 61
TPrA1860.04571-b −1.34090  ± 28
TBuMA2000.07441-a −1.12866  ± 24
TBA2420.77261-b −0.11252  ± 19
TPeA29813.06051-b 1.1168.6  ± 2.2
THA354220.7881-b 2.3443.0  ± 1.6
  • IC50 values were obtained by fitting data from two to four separate experiments (e.g., Fig. 3) as described inExperimental Procedures and are presented as means ± S.D.

  • 1-a P values measured by Neef and Meijer (1984).

  • 1-b P values derived from Neef and Meijer (1984).