Table 1

Effect of membrane depolarization (120 mmol of K+) and inhibition of cytochrome P-450 (thiopental/miconazole) on relaxation by CRF

ED50 (log mol)Area Under Curve (arbitrary unit)
NE−7.73  ± 0.07129.74  ± 13.54
120 mmol of K+ −7.56  ± 0.0770.22  ± 6.06*
NE/thiopental−7.61  ± 0.0583.86  ± 4.45*
NE/miconazole−7.64  ± 0.0683.84  ± 6.25*

One-way analysis of variance followed by Newman–Keuls multiple comparisons test was used, *p < .05, versus NE.