Quantification of cellular infiltrate of DNFB-sensitized skin sites in C3H/HeN, wild-type, and IL-5 transgenic mice
| Cells | Wild-type mice | IL-5 transgenic mice | p value |
|---|---|---|---|
| Total cells | 16.1 ± 1.99 | 139.3 ± 16.6 | 0.001 |
| Eosinophils | 2.9 ± 0.52 | 116.0 ± 14.8 | 0.001 |
| Neutrophils | 5.3 ± 1.02 | 10.9 ± 1.54 | 0.001 |
| Mononuclear cells | 7.9 ± 1.06 | 12.4 ± 1.82 | N.S. |
Mean (±S.E.M.) values are cells per HPF (200×) from 18 HPFs. Samples were obtained 24 h after fifth painting with DNFB. Mean number of total cells in naive or vehicle-treated mice (wild-type and IL-5 transgenic mice) is under 1.8/HPF.