Table 1

Effect of acute ethanol treatment and GdCl₃ in vivo on ketogenesis in the perfused liver

Treatment	Ketogenesis β-Hydroxybutryrate + Acetoacetate
	μmol/g/h
Control	11.4 ± 0.4
Ethanol	27.7 ± 5.5^1-a
GdCl₃	12.5 ± 1.7
GdCl₃ + ethanol	12.3 ± 4.5^1-b

Ethanol or saline was given i.g. 2.5 h before perfusion to fed rats after treatment in vivo with 10 mg/kg GdCl₃ or saline i.v. 24 h before perfusion as described in the text. Livers were perfused for 20 min, and acetoacetate (A) and β-hydroxybutryrate (B) were determined enyzmatically in samples of effluent perfusate (Bergmeyer, 1988). Results are expressed as mean ± S.E.M.,n = 5–7. Statistical comparisons were made using two-way ANOVA on ranks and Tukey’s post hoc test.

↵1-a p < .05 for comparison with the control group.
↵1-b p < .05 for comparison with the ethanol group.