Organic cations tested for substrate specificity in avian renal BBMV
| pKa | M.W. | ||
|---|---|---|---|
| Endobiotic compounds | |||
| Acetylcholine (ACh) | 13 | 146.2 | Acara and Rennick (1972) |
| Choline | 13.9 | 104.2 | Acara and Rennick (1973) |
| Epinephrine | 9.95 | 183.2 | Rennick and Yoss (1962) |
| Guanidine | 13.6 | 59.1 | Sperber (1948) |
| N1-Methylnicotinamide (NMN) | 13 | 137.2 | Sperber (1948) |
| Serotonin | 11.1 | 176.2 | Sanner and Wortman (1962) |
| Thiamine | 9.2 | 301.8 | Rennick et al. (1984) |
| Xenobiotic compounds | |||
| Amiloride | 8.7 | 229.7 | Rennicket al. (1984) |
| Cimetidine | 7.1 | 252.3 | Rennicket al. (1984) |
| Isoproterenol | 10.4 | 211.2 | Lifshitz et al.(1973) |
| Mepiperphenidol (Darstine) | >13 | 370.4 | Pilkington and Keyl (1963) |
| Procainamide | 9.2 | 236.4 | Christianet al. (1984) |
| Quinidine | 8.8 | 324.4 | Gerhardtet al. (1969) |
| Quinine | 8.5 | 324.4 | Haag et al. (1943) |
| Ranitidine | 8.2 | 314.4 | McNeil et al. (1981) |
| Tetraethylammonium | 13 | 130.3 | Rennicket al. (1984) |
Names, abbreviations or common name, dissociation constants (pKa) and molecular weights (M.W.) are listed.
Representative citations for net tubular secretion are given in parentheses.