Compound | 3H[AA] release (% of control) | |
---|---|---|
Control | +RHC-80267 | |
Bradykinin | 142 ± 11 | 90 ± 63-150 |
Pardaxin | 310 ± 13 | 288 ± 15 |
PC12 cells were labeled with [3H]AA, washed and treated or not treated with RHC-80267 (50 μM) for 30 min. The cells were then incubated for an additional 15 min with Pardaxin (5 μM) or 30 min with bradykinin (1 μM).
The results are the mean ± S.E.M. of three experiments (n = 3).
↵3-150 P < .05 vs. agent alone.