Effects of MK-801 on eticlopride-induced zif268 expression in the striatum
| Treatment | Medial | Central | Lateral |
|---|---|---|---|
| Control (5) | 32.1 ± 1.7 | 27.5 ± 1.3 | 28.6 ± 2.5 |
| MK-801 (5) | 23.6 ± 2.6 | 21.5 ± 2.4 | 26.2 ± 2.8 |
| Eticlopride (3) | 45.3 ± 4.6 | 49.7 ± 2.42-a | 70.1 ± 7.52-a |
| 0.01 mg/kg MK-801 + eticlopride (4) | 50.3 ± 2.22-a | 52.2 ± 3.22-a | 57.9 ± 3.82-a |
| 0.1 mg/kg MK-801 + eticlopride (5) | 45.3 ± 4.3 | 47.1 ± 5.42-a | 59.7 ± 3.82-a |
| 1 mg/kg MK-801 + eticlopride (5) | 39.0 ± 3.4 | 48.2 ± 4.72-a | 56.6 ± 4.92-a |
Values are mean gray values (±S.E.M.; arbitrary units) obtained from densitometric analysis of the medial, central and lateral thirds of the mid-striatum (0.5 mm anterior to bregma). Numbers in parentheses are the number of animals per group.
↵2-a Significantly different from control, P < .05.
2-b Significantly different from eticlopride alone, P < .05.