Effects of CGS 19755 on eticlopride-induced zif268expression in the striatum
| Treatment | Medial | Central | Lateral |
|---|---|---|---|
| Control (5) | 29.7 ± 1.6 | 26.9 ± 1.3 | 30.9 ± 1.9 |
| CGS 19755 (5) | 20.8 ± 1.7 | 21.3 ± 2.0 | 23.9 ± 2.1 |
| Eticlopride (4) | 49.8 ± 1.41-a | 53.5 ± 2.11-a | 60.9 ± 2.41-a |
| 1 mg/kg CGS 19755 + eticlopride (5) | 41.6 ± 3.01-a | 45.6 ± 3.51-a | 55.3 ± 2.91-a |
| 5 mg/kg CGS 19755 + eticlopride (5) | 32.9 ± 2.31-b | 39.7 ± 3.1a,b | 51.8 ± 3.41-a |
| 10 mg/kg CGS 19755 + eticlopride (5) | 30.6 ± 2.41-b | 39.6 ± 3.5a,b | 52.5 ± 4.51-a |
Values are mean gray values (±S.E.M.; arbitrary units) obtained from densitometric analysis of the medial, central and lateral thirds of the mid-striatum (0.5 mm anterior to bregma). Numbers in parentheses are the number of animals per group.
↵1-a Significantly different from control, P < .05.
↵1-b Significantly different from eticlopride alone, P < .05.