Table 3

Effect of β3-AR agonist treatment on lipolysis in WT mice

GroupPlasma Glycerol (mM)
Vehicle0.646  ± 0.019
BRL 351351.372  ± 0.027*
CL 316,2431.132  ± 0.054*
ICI 198,1570.948  ± 0.043*
  • Nonfasted mice received injections s.c. with 3 mg/kg of compound and plasma glycerol levels were determined 60 min later. Values are the mean ± S.E.M. (n = 5). *P <.001 in comparison to vehicle-treated control group.