Enhancement of anti-HEL IgG antibody production by DEP administered after immunization with HEL
| Duration | Anti-HEL IgG Antibody (A405) | |
|---|---|---|
| PBS | DEP | |
| Days −5 to −1 | 0.51 ± 0.04 | 0.53 ± 0.06 |
| Days 0 to 5 | 0.47 ± 0.06 | 0.62 ± 0.07 |
| Days 0 to 10 | 0.56 ± 0.06 | 0.88 ± 0.072-a |
| Days 0 to 20 | 0.50 ± 0.04 | 1.22 ± 0.092-a |
Daily mice were given PBS or 1 mg of DEP orally on the indicated days before or after immunization with HEL on day 0. Serum samples were collected on day 21 and assayed for anti-HEL IgG antibodies by ELISA as described in “Materials and Methods.” Values are shown as mean ± S.E.M. of five mice.
↵2-a P < .05 vs. PBS (Student’s ttest).