Regression analysis (r2) of the relationship between U-89678 consumption and the sample to sample variation of selected cytochrome P450 activities across a population of human livers (n = 9)
| Cytochrome P450 enzyme | Regression coefficient (r2) |
|---|---|
| CYP1A2 | 0.025 |
| CYP2A6 | 0.056 |
| CYP2C9 | 0.075 |
| CYP2C19 | 0.017 |
| CYP2D6 | 0.315 |
| CYP2E1 | 0.027 |
| CYP3A4 | 0.869 |
The best regression coefficient for U-89678 metabolism is represented in bold.