Table 6

Effects of YM158, seratrodast and daltroban on U46619-induced aggregation of guinea pig and human platelets

PlateletsIC50 (95% CL) [nM]
YM158SeratrodastDaltroban
Guinea pig290270350
(170–490)(180–400)(210–630)
Human53022000140
(500–570)(550–61000)  (110–190)
  • Values represent the mean with 95% CL of 3 to 5 experiments.