Table 1

Equilibrium dissociation constants (K_d values) and maximal binding site density (B_max values) determined from [³H]5-HT and [³H]LSD saturations using membranes harvested from cells stably expressing the recombinant human 5-HT_7(a) receptor

Radioligand	K_d (nM)	B_max (fmol/mg prot.)
[³H]5-HT	2.9 ± 0.4	163 ± 35
[³H]LSD	4.0 ± 0.6	189 ± 36

Binding parameters represent mean ± S.E. of three to five determinations.