Maximal responses and pD2 values to vasopressin and pA2 and slope values of Schild plots of the antagonism of d(CH2)5Tyr(Me)AVP (V1 antagonist) in human penile dorsal arteries and veins
| Vasopressin | V1 antagonist | |||
|---|---|---|---|---|
| Maximal contraction | pD2 | pA2 | Slope | |
| % | ||||
| Artery (n = 6) | 141 ± 9 | 9.38 ± 0.18 | 8.98 ± 0.08 | 0.97 ± 0.07 |
| Vein (n = 6) | 110 ± 4 | 9.40 ± 0.14 | 8.96 ± 0.05 | 1.05 ± 0.04 |
Values are mean ± S.E. Maximal contraction is expressed as a percentage of response to 100 mM KCl.
n, number of patients.