Angiotensin II and U46619-induced pulmonary artery pressure (PAP) responses
| Challenge | ||||||
|---|---|---|---|---|---|---|
| First 0 min (mmHg) | S.E.M. | Second 30 min (mmHg) | S.E.M. | Third 60 min (mmHg) | S.E.M. | |
| Angiotensin II (30 nmol/liter) | 2.78 | 0.45 | 2.60 | 0.46 | 3.80 | 0.72 |
| Angiotensin II (30 nmol/liter) | 2.93 | 0.80 | 2.25 | 0.49 | 2.20 | 0.31 |
| NS-398 (25 μmol/liter) | ||||||
| U46619 (2.5 nmol/liter) | 4.48 | 1.35 | 5.58 | 1.31 | 6.00 | 1.18 |
| U46619 (2.5 nmol/liter) | 4.10 | 0.42 | 5.23 | 0.42 | 5.03 | 0.32 |
| NS-398 (25 μmol/liter) | ||||||
Statistical analysis showed no significant difference between the challenges without and with inhibitor.