Table 2

Effects of 100 μM methohexital on holding currents and conductance

		Before	Methohexital
Hippocampal CA1 neurons
In standard ACSF (n = 13)	Holding current (pA)	55.4 ± 18.5	149.8 ± 56.3^2-b
	Conductance (pS)	9.6 ± 0.5	17.3 ± 2.7^2-b
In bicuculline^2-a (n = 11)	Holding current (pA)	39.7 ± 19.5	56.9 ± 24.7
	Conductance (pS)	13.4 ± 0.8	14.5 ± 0.9
Cortical neurons (n = 9)
In standard ACSF	Holding current (pA)	15.1 ± 45.2	22.3 ± 69.1
	Conductance (pS)	7.6 ± 0.8	12.5 ± 1.0^2-b

↵2-a Bicuculline (10 μM) was applied throughout the recording period.
↵2-b Paired Student’s t test, P < .05.