Summary table showing the effects of several drugs upon the DRL 72-sec reinforcement rate of Harlan and Holtzman rats
| DRUG (dose) | Reinforcement Rate | |
|---|---|---|
| Harlan | Holtzman | |
| 8-OH-DPAT (0.05, 0.1, 0.2 mg/kg, sc) | ⇓⇓ | ⇑⇑ |
| Imipramine (2.5, 5.0, 10.0 mg/kg, ip) | | ⇑ |
| Ketanserin (1.0, 3.0, 10.0 mg/kg, ip) | | ⇑ |
| Fluoxetine (5.0, 10.0, 20.0 mg/kg, ip) | | ⇑⇑⇑ |
| Desipramine (1.25, 2.5, 5.0, 10.0 mg/kg, ip) | ⇑⇑⇑ | ⇑⇑⇑ |
| Amphetamine (1.0 and 1.5 mg/kg, ip) | ⇓⇓ | ⇓⇓ |
The doses of each drug are listed; the number of “⇑” or “⇓” symbols indicates the number of doses in which the reinforcement rate increased or decreased, respectively. “” indicates that no significant effect of the drug was observed at any dose.