Treatment effects on different parameters in rats from experiment 2
| Group | Weight before surgery | Weight before death | Uterine wet weight | Uterus/body mass ratio | ||
|---|---|---|---|---|---|---|
| g | mg | |||||
| Intact control | 221 ± 7 | 202 ± 6 | 382 ± 1082-a | 19 ± 62-a | ||
| OVX control | 227 ± 10 | 218 ± 22 | 155 ± 14 | 7 ± 0.3 | ||
| OVX | +4-OHE2 (0.05 mg/kg) | 222 ± 5 | 203 ± 26 | 216 ± 98 | 16 ± 72-a | |
| OVX | +4-OHE2 (0.5 mg/kg | 224 ± 7 | 200 ± 12 | 343 ± 372-a | 17 ± 12-a | |
| OVX | +4-OHE2 (0.5 mg/kg) | +4-OHT (1.5 mg/kg) | 222 ± 3 | 199 ± 9 | 239 ± 482-a | 12 ± 32-a |
| OVX | +2-OHE2 (0.5 mg/kg) | 221 ± 7 | 212 ± 12 | 155 ± 10 | 7 ± 0.8 | |
| OVX | +E2 (0.5 mg/kg) | 220 ± 4 | 205 ± 16 | 421 ± 1452-a | 21 ± 82-a | |
| OVX | +E2 (0.5 mg/kg) | +4-OHT (1.5 mg/kg) | 225 ± 4 | 204 ± 8 | 256 ± 442-a | 13 ± 22-a |
| OVX | +2-meoE1 (0.5 mg/kg) | 227 ± 8 | 199 ± 21 | 150 ± 10 | 8 ± 1 | |
| OVX | +2-meoE2 (0.5 mg/kg) | 222 ± 9 | 200 ± 18 | 141 ± 10 | 7 ± 0.6 | |
The interval between surgery and the beginning of treatment was 7 days. Results are presented as mean ± S.D.
↵2-a P < .05 compared with OVX control.