Table 1

Paw volumes (ml) after solvent, capsaicin (150 mg/kg s.c.) or 6-OHDA (225 mg/kg i.p.) pretreatment in rats with unilateral FCA-induced hindpaw inflammation

Noninflamed PawsInflamed PawsInflamed/ Noninflamed (%)n
Solvent3.35  ± 0.095.21  ± 0.161-a 155.87  ± 4.538
Capsaicin3.45  ± 0.115.16  ± 0.171-a 149.60  ± 3.137
Solvent3.59  ± 0.086.43  ± 0.371-a 178.63  ± 8.538
6-OHDA3.44  ± 0.075.74  ± 0.121-a 167.02  ± 4.228
  • Data are expressed as mean ± S.E.M.

  • 1-a P < .001 indicate significant differences between inflamed and non-inflamed paws (Wilcoxon test).