Table 3

Pearson’s product-moment correlation between the dextromethorphan metabolic ratio from each multiple-dose sampling method (the y-axis) and that from the corresponding single-dose method (the x-axis)

ParameterCorrelation CoefficientP ValueSlopeInterceptNo.
0–2 h urine0.89940.00582.9840.0167
0–4 h urine0.95210.00011.0830.0859
0–6 h urine0.97220.00011.2490.0719
0–8 h urine0.93780.00021.1640.2679
0–12 h urine0.96520.00011.1780.2009
0–24 h urine0.94010.00022.1150.0489
1 h plasma0.64730.23770.9470.5895
1.5 h plasma0.75280.05081.0380.4857
2 h plasma0.89460.01611.7370.0886
3 h plasma0.82030.01260.8650.4208
4 h plasma0.94250.00011.0400.1879
5 h plasma0.82870.02120.4250.4987
6 h plasma0.61580.14100.6260.4767
8 h plasma0.57440.31110.3810.9045
AUC0.80490.00902.4260.5239
6 h saliva0.89900.01480.7840.7176