Table 1

Pearson’s product-moment correlations between the dextromethorphan metabolic ratio of AUC (they-axis) and those of other parameters (thex-axis) in the single-dose study

ParameterCorrelation CoefficientP ValueSlopeInterceptNo.
0–2 h urine0.78720.01181.8180.1309
0–4 h urine0.84180.00060.7560.16212
0–6 h urine0.85490.00060.8510.15012
0–8 h urine0.85500.00040.8810.14712
0–12 h urine0.85780.00040.8850.14412
0–24 h urine1.00000.00012.0000.00012
1 h plasma0.98490.00010.2590.0237
1.5 h plasma0.97220.00010.4450.01910
2 h plasma0.96330.00010.3830.01210
3 h plasma0.86660.00120.2910.03510
4 h plasma0.81390.00230.2840.01511
5 h plasma0.94460.00010.1930.0639
6 h plasma0.78940.01140.274−0.0509
8 h plasma0.95060.00360.206−0.0126
2 h saliva0.80820.00260.149−0.00711
6 h saliva0.81800.00710.0560.0919