List of nontachykinin receptor binding assays performed to determine selectivity of PD 156982 for tachykinin NK₁receptors. Assays were carried out using standard methodology as described in the literature. PD 156982 showed <50% inhibition of specific binding at 10 μM in the majority of assays. Of the exceptions, highest affinity was observed at CCK_A receptors in the rat pancreas [IC₅₀ value 450 nM (range 270–600)]. IC₅₀ values in the 2 to 10 μM range were obtained for human BB₁ and BB₂ receptors, CCK_B and 5-HT₂receptors and calcium channels labeled by [³H]-nimodipine.