Table 2

Effects of E4031, 10−6 M, on number and amplitude of EAD, in placebo-, estrogen-, and DHT-treated hearts

Number of EADsAmplitude of EAD
msec
Placebo (n = 15)0.7  ± 0.33.2  ± 1.5
EST (n= 12)1.9  ± 0.52-a 14.3  ± 4.12-a
DHT (n = 8)0.5  ± 0.42.5  ± 1.7
  • CL = 2000 msec.

  • 2-a P < .05, compare placebo with DHT.