Effect of TGF-β1 and IL-10 on Dex IC50 in anti-CD3-induced T cell proliferation1-a
| Cytokine Concentration | Dex + TGF-β1 IC50 | Dex + IL-10 IC50 |
|---|---|---|
| nM | ||
| 0 | 393 ± 57 | 393 ± 57 |
| 0.0005 | 361 ± 56* | 360 ± 61* |
| 0.0050 | 77 ± 2** | 30 ± 2** |
| 0.0500 | 12 ± 1** | <1 |
| 0.5000 | <1 | <1 |
↵1-a Results from one of four experiments are expressed as means ± S.D. of triplicate determinations. IC50 = the concentration resulting in a 50% inhibition of T cell proliferation.
* P = N.S.; ** P < .01.