Table 6

Effects in phase 2 of the formalin test of naltrexone pretreatment on the antinociceptive effect of ABT-594 (n = 4–12/group)

GroupResponses6-a
sal/sal32.7  ± 7.1
ntx/sal54.0  ± 9.9
sal/ABT-5946.4  ± 4.0*
ntx/ABT-5944.8  ± 3.4*
  • 6-a Values are mean ± S.E.M.

  • * P < .05 vs. sal/sal.