Table 2

Effects in the hot box of mecamylamine pretreatment on the antinociceptive effect of ABT-594 (n = 8/group)

GroupLatency(s) ± S.E.M.
sal/sal11.4  ± 1.1
mec/sal10.2  ± 0.8
sal/ABT-59417.6  ± 1.0*
mec/ABT-59411.6  ± 1.7‡
  • * P < .05 vs. sal/sal.

  • ‡ P < .05 vs. sal/ABT-594.