Vehicle | Glibenclamide | |
---|---|---|
Body weight (g) | 247 ± 4 | 244 ± 4 |
Left kidney weight (g) | 0.99 ± 0.05 | 1.01 ± 0.04 |
MABP (mm Hg) | 101 ± 4 | 101 ± 3 |
PCV | 0.46 ± 0.01 | 0.45 ± 0.01 |
PNa (mM) | 139 ± 2 | 136 ± 1 |
PK (mM) | 4.2 ± 0.1 | 4.3 ± 0.2 |
Values are means ± S.E. n = 8 in each group. Packed cell volume and plasma data were measured on the final blood sample. MABP, Mean arterial blood pressure; PCV, packed cell volume; PNa,PK, plasma sodium and potassium concentration respectively.