Control | Fendiline | |
---|---|---|
Mean current (pA) | 0.56 ± 0.15 | 0.32 ± 0.09* |
Unitary current amplitude (pA) | 1.62 ± 0.08 | 1.64 ± 0.10N.S. |
Channel availability | 0.72 ± 0.06 | 0.66 ± 0.06* |
Open probability | 0.44 ± 0.08 | 0.29 ± 0.05* |
Mean open time (msec) | 6.34 ± 0.46 | 4.46 ± 0.56** |
Mean shut time (msec) | 3.55 ± 0.25 | 6.22 ± 0.63* |
Mean openings/record | 5.95 ± 0.55 | 4.55 ± 0.63N.S. |
Latency-to-first-event (msec) | 8.22 ± 1.70 | 13.9 ± 2.36N.S. |
Values are means ± S.E.M. of five experiments.
* P < .05; ** P < .01.