Body and organ weights of BALB/c mice treated with fumonisin B1for 5 days
| Parameter | Fumonisin B1 dose | ||||
|---|---|---|---|---|---|
| 0 | 0.25 | 0.75 | 2.25 | 6.75 | |
| mg/kg/day | |||||
| Initial body weight (g) | 23.83 ± 0.17 | 22.83 ± 0.40 | 23.50 ± 0.50 | 23.00 ± 0.58 | 23.50 ± 0.76 |
| Final body weight (g) | 24.17 ± 0.11 | 23.42 ± 0.40 | 23.58 ± 0.54 | 22.75 ± 0.66 | 23.42 ± 0.72 |
| Organ weights | |||||
| Liver (g) | 1.413 ± 0.036 | 1.342 ± 0.040 | 1.375 ± 0.038 | 1.330 ± 0.049 | 1.408 ± 0.067 |
| Kidney (mg) | 408.52 ± 6.26 | 331.13 ± 5.901-a | 325.23 ± 11.571-a | 306.37 ± 9.341-a | 319.98 ± 13.151-a |
| Thymus (mg) | 40.15 ± 1.37 | 41.73 ± 2.82 | 38.07 ± 3.05 | 41.00 ± 3.29 | 38.30 ± 2.61 |
| Spleen (mg) | 83.97 ± 2.22 | 73.65 ± 2.99 | 82.17 ± 3.60 | 81.97 ± 2.80 | 81.52 ± 1.51 |
| Brain (mg) | 414.30 ± 6.47 | 429.50 ± 2.54 | 415.32 ± 7.48 | 422.58 ± 5.98 | 421.05 ± 8.70 |
| Kidney/Body wt. (mg/g) | 16.91 ± 0.27 | 14.15 ± 0.231-a | 13.78 ± 0.271-a | 13.47 ± 0.121-a | 13.65 ± 0.271-a |
Values are given as mean ± S.E.M. (n = 6).
↵1-a Significantly different from the control value (P < .0001).