Table 1

Brain and plasma levels of cocaine and metabolites

Day	Brain Level (ng/g brain tissue)		Plasma Level (ng/ml)
Day	Cocaine	EME	BE	Cocaine	EME	BE
1	239 ± 28	318 ± 84	95 ± 24	466 ± 75	37 ± 14	34 ± 5
2	171 ± 38	286 ± 60	128 ± 5	339 ± 33	71 ± 7^1-a	32 ± 4
3	259 ± 42	210 ± 43	106 ± 10	317 ± 71	57 ± 5	29 ± 4
4	196 ± 19	152 ± 39	100 ± 7	361 ± 76	65 ± 5^1-a	28 ± 3
5	253 ± 48	205 ± 73	107 ± 13	349 ± 45	70 ± 8^1-a	30 ± 2
6	228 ± 18	167 ± 21	119 ± 13	425 ± 60	73 ± 7^1-a	30 ± 2
7	247 ± 16	166 ± 18	99 ± 10	367 ± 48	73 ± 7^1-a	30 ± 2

↵1-a P ≤ .05, compared to day 1.