Effect of acetylenic and dibromo olefinic fatty acid analogs on arachidonic acid ω-hydroxylation and epoxidation in rat renal cortical microsomes
| Compound | IC50 (μM) | |
|---|---|---|
| ω-Hydroxylation | Epoxidation | |
| PPOH | >200 | 9 |
| MS-PPOH | >200 | 13 |
| DPMS | 31 | >100 |
| DDMS | 2 | 60 |
| DBDD | 2 | 51 |
| 17-ODYA | 7 | 5 |