[Strychnine] (μM) | Rise Time (% of Control) | Decay-Time Constant (τ) (% of Control) |
---|---|---|
0.3 | 107 ± 11 (6)3-a | 126 ± 5 (6) |
1 | 132 ± 18 (4) | 188 ± 12 (4) |
3 | 168 ± 26 (4) | 388 ± 138 (4) |
↵3-a Mean ± S.E.M. (number of neurons). Under control conditions, the rise time of ACh (0.3 mM)-evoked type IA currents ranged from 15 to 27 msec (n = 14). The decay phase of currents recorded from 11 neurons was best fitted by a single-exponential function and the decay-time constant of these currents ranged from 15.2 to 52.1 msec. The decay phase of the currents recorded from three neurons was fitted by a double-exponential function, and the τf of these currents, which varied from 14.6 to 22.7 msec, was used in averaging the results.