Table 2

Effect of strychnine on the apparent potency for ACh in eliciting type IA current

ConditionEC50(mM)Hill Coefficient (nH)
ACh0.41  ± 0.032-a 1.2  ± 0.1
ACh + strychnine (2 μM) in U-tube0.80  ± 0.051.3  ± 0.1
ACh + strychnine (2 μM) in the U-tube and the bath0.78  ± 0.101.2  ± 0.1
  • 2-a Mean ± S.E.M.