Vh (l) | kout(l/min) | PS (l/min) | Vdeep(l) | R2 | MSC | |
---|---|---|---|---|---|---|
(+)-Enantiomer | ||||||
Flow | 1.11 | 0.992 | 4.14 | |||
(1.01–1.22) | ||||||
Flow + loss | 1.09 | 0.01 | 0.992 | 4.15 | ||
(0.98–1.22) | (−0.007–0.030) | |||||
Membrane | 1.10 | 0.01 | >103 | 0.992 | 4.11 | |
(0.99–1.21) | (−0.004–0.028) | |||||
(−)-Enantiomer | ||||||
Flow | 1.13 | 0.992 | 4.25 | |||
(1.00–1.26) | ||||||
Flow + loss | 1.09 | 0.02 | 0.995 | 4.43 | ||
(0.97–1.21) | (0.007–0.040) | |||||
Membrane | 1.09 | 0.02 | >103 | 0.997 | 4.38 | |
(0.98–1.20) | (0.001–0.046) |
The parameters of the flow-limited (flow), flow-limited with first-order loss (flow + loss) and membrane-limited (membrane) myocardial kinetic models for each enantiomer. Goodness of fit is given by the R2 value and the MSC (see the text). A higher MSC indicates a better fit. The data are shown as the mean and upper and lower 95% confidence limits. There were no statistically significant differences between the means for each enantiomer by comparison of the means and 95% confidence limits.