Ability of HDL and LDL to bind 3H-CE1-a and3H-CSA1-b after a 24-hr incubation in human plasma at 37°C
| Lipoprotein Fraction | 3H-CE (pg of 3H-CE/μg of Cholesterol) | 3H-CSA (ng of 3H-CSA/μg of Cholesterol) |
|---|---|---|
| HDL | 2.6 ± 1.0 | 0.48 ± 0.16 |
| LDL | 2.2 ± 1.1 | 0.20 ± 0.081-c |
Abbreviations: HDL, high-density lipoproteins; LDL, low-density lipoproteins; 3H, tritum; CE, cholesteryl esters; CSA, cyclosporine. Data are presented as mean ± S.D. (n = 6).
↵1-a 13.9 ng of 3H-cholesteryl ester was incubated in 1 ml of human plasma.
↵1-b 1000 ng of 3H-cyclosporine was incubated in 1 ml of human plasma with an endogenous lipid transfer protein I concentration of 1.0 μg protein/ml.
↵1-c P < .05 vs. HDL.