Table 2

Comparison of the mean transit times of noneliminated references and their distribution volumes in the MID studies in EHBR and SDR

	Mean transit times^2-a		Distribution space		γ_Alb	γ_Sue	γ_D₂_O	θ^2-b	t₀
	RBC	Albumin	Sucrose	Water	γ_Alb	γ_Sue	γ_D₂_O	θ^2-b	t₀	Blood volume V_sin	Albumin Disse V_I,Alb	Sucrose Disse V_I,Suc	Cell water space V_cell
	sec	sec	sec	sec	ml/g	ml/g	ml/g	ml/g
EHBR (n = 10)	19 ± 2.9	26 ± 4.1	29 ± 4.8	65 ± 4.4	0.28 ± 0.04	0.08 ± 0.02	0.12 ± 0.02	0.48 ± 0.04	0.61 ± 0.07	0.93 ± 0.10	5.4 ± 1.1	5.1 ± 1.2	1.5 ± 0.8^2-d
SDR^2-c(n = 12)	15 ± 3.2	19 ± 4.5	23 ± 4.5	60 ± 10	0.23 ± 0.05	0.06 ± 0.02	0.11 ± 0.03	0.57 ± 0.06	0.51 ± 0.12	0.83 ± 0.20	6.4 ± 2.0	6.3 ± 2.2	4.1 ± 1.1

↵2-a Corrected for inflow and outflow catheters, with the deconvolution procedure.
↵2-b Ratio of cellular water to sinusoidal plasma space; θ was calculated as = γ_D₂₀ × [f_p (1 − Hct) + f_rHct]/[f_p (1 − Hct)] − γ_Suc, where f_p and f_r are the water contents of plasma and RBC, respectively.
↵2-c Data for SDR rats were taken from Geng et al.(1995b).
↵2-d P < .05, different from SDR.