Pharmacokinetic parameters derived from one-compartment model in pregnant sheep
| Parameter | Sheep | Mean | S.E.M. | |||
|---|---|---|---|---|---|---|
| 9391 | 9341 | 9051 | 9041 | |||
| Vd(ml/kg) | 80.2 | 37.9 | 66.1 | 52.5 | 59.2 | 7.9 |
| k 10(h−1) | 0.327 | 0.527 | 0.343 | 0.496 | 0.423 | 0.045 |
| Cl (ml/kg/hr) | 26.2 | 20.0 | 22.7 | 26.0 | 23.7 | 1.3 |
| t½ (hr) | 2.1 | 1.3 | 2.0 | 1.4 | 1.7 | 0.2 |